Genes that Escape Silencing on the Second X Chromosome May Drive Disease
Por um escritor misterioso
Last updated 22 dezembro 2024
When X-linked genes evade silencing on the “inactive” chromosome in XX cells, some protect women from diseases such as cancer, but others seem to promote conditions such as autoimmunity.
A lifelong duty: how Xist maintains the inactive X chromosome - ScienceDirect
X-linked gene dosage contributes to sex disparities in disease.
Frontiers Why Females Do Better: The X Chromosomal TLR7 Gene-Dose Effect in COVID-19
Frontiers Recent Advances in Understanding the Reversal of Gene Silencing During X Chromosome Reactivation
Escaping but not the inactive X-linked protein complex coding genes may achieve X-chromosome dosage compensation and underlie X chromosome inactivation-related diseases - ScienceDirect
Attrition of X Chromosome Inactivation in Aged Hematopoietic Stem Cells - ScienceDirect
PDF) Long noncoding RNA XIST: Mechanisms for X chromosome inactivation, roles in sex-biased diseases, and therapeutic opportunities
Gracefully ageing at 50, X-chromosome inactivation becomes a paradigm for RNA and chromatin control
Skewed X-inactivation is common in the general female population
Cross-species examination of X-chromosome inactivation highlights domains of escape from silencing, Epigenetics & Chromatin
Long noncoding RNA XIST: Mechanisms for X chromosome inactivation, roles in sex-biased diseases, and therapeutic opportunities - ScienceDirect
X chromosome escape maps differ between mouse tissues. The position of
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