A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia - ScienceDirect

Inhibition of the Menin (MEN1) and MLL (MLL1, KMT2A) interaction is a potential therapeutic strategy for MLL-rearranged (MLL-r) leukemia. Structure-ba…

Co-inhibition of HDAC and MLL-menin interaction targets MLL

Novel therapeutic strategies for MLL-rearranged leukemias

Discovery of M-1121 as an Orally Active Covalent Inhibitor of

A Menin-MLL Inhibitor Induces Specific Chromatin Changes and

A Menin-MLL Inhibitor Induces Specific Chromatin Changes and

Epigenetic deregulation in myeloid malignancies - ScienceDirect

MLL::AF9 degradation induces rapid changes in transcriptional

High-Affinity Small-Molecule Inhibitors of the Menin-Mixed Lineage

Pharmacologic Inhibition of the Menin-MLL Interaction Blocks

Learning from mouse models of MLL fusion gene-driven acute

A Menin-MLL Inhibitor Induces Specific Chromatin Changes and

A Menin-MLL Inhibitor Induces Specific Chromatin Changes and

Synergistic targeting of FLT3 mutations in AML via combined menin