BRCA2 promotes DNA‐RNA hybrid resolution by DDX5 helicase at DNA

Summary of the themes regarding DDX RNA helicase involvement in genome

BRCA2 promotes DNA‐RNA hybrid resolution by DDX5 helicase at DNA breaks to facilitate their repair‡

RNAPII response to transcription‐blocking DNA lesions in mammalian cells - Wang - 2023 - The FEBS Journal - Wiley Online Library

Sources, resolution and physiological relevance of R-loops and RNA–DNA hybrids

Resolution of R-loops by topoisomerase III-β (TOP3B) in coordination with the DEAD-box helicase DDX5 - ScienceDirect

Role of the DEAD-box RNA helicase DDX5 (p68) in cancer DNA repair, immune suppression, cancer metabolic control, virus infection promotion, and human microbiome (microbiota) negative influence

p68 RNA Helicase Antibody (A-5) SCBT - Santa Cruz Biotechnology

PDF] R-loops: formation, function, and relevance to cell stress

Looping out of control: R-loops in transcription-replication conflict

DNA:RNA Hybrids in DNA Repair

Full article: A new interaction between BRCA2 and DDX5 promotes the repair of DNA breaks at transcribed chromatin

DNA-RNA hybrids at DSBs interfere with repair by homologous recombination

Cancers, Free Full-Text

Frontiers Making Connections: Integrative Signaling Mechanisms Coordinate DNA Break Repair in Chromatin

ZFP281-BRCA2 prevents R-loop accumulation during DNA replication