Dissecting MENIN in bivalent gene regulation

Publications — Greenleaf Lab @ Stanford

The chromatin signature of pluripotent cells

Epigenetic regulation of T cells by Polycomb group proteins - Melo - 2022 - Journal of Leukocyte Biology - Wiley Online Library

MIT Computational Biology Group

Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes. - Abstract - Europe PMC

Mll2 binds to most H3K4me3 promoters, including bivalent promoters. (A)

Dissecting the Kinetic Mechanism of Human Lysine Methyltransferase 2D and Its Interactions with the WRAD2 Complex

Full article: Bivalent Epigenetic Control of Oncofetal Gene Expression in Cancer

Epigenetic mechanisms involved in developmental nutritional programming

Frontiers Is There a Histone Code for Cellular Quiescence?

Dissecting the Kinetic Mechanism of Human Lysine Methyltransferase 2D and Its Interactions with the WRAD2 Complex

Epigenetic regulation of B cell fate and function during an immune response - Zhang - 2019 - Immunological Reviews - Wiley Online Library

IJMS, Free Full-Text

Rescue strategy for dissecting Mll2 activities in mESC (A) Top panel

Dissecting the Kinetic Mechanism of Human Lysine Methyltransferase 2D and Its Interactions with the WRAD2 Complex